How The AVACEN 100 Works
 
When the hand, enclosed in a special patented mitt, is placed inside the vacuum chamber, the microprocessor manages the application of negative pressure and heat to safely increase the temperature and volume of blood flowing through the high volume AVA’s. It is important to note that the application of heat without negative pressure is ineffective.
 
Heat
Infusing heat into the circulatory system reduces blood thickness (viscosity) and increases microcirculation. Thinner blood facilitates more efficient flow through the skeletal muscles on its route to the smaller vasodilated capillaries (microvascular circulation) which the body uses to radiate the excess ATM produced heat into the cooler ambient air.
 
Microcirculation Boost
An increase in microcirculation enhances oxygen delivery and nutrition to the skeletal muscles while carrying away toxins. The result… healthier, more relaxed muscles throughout the entire body.
 
Opens the atrial/veinus anastomosis to allow the safe exchange of heat and decrease blood viscosity. Stimulates capillary bed production. Aids in the release of endorphins to naturally control pain. Temporarily increase microcirculation to aid in the relief of minor muscle and joint pain and stiffness and the temporary relief of joint pain associated with conditions such as arthritis and fibromyalgia.
 
U.S. FDA-Clearance:  as a heat therapy system indicated for the temporary relief of minor muscle and joint pain and stiffness; the temporary relief of joint pain associated with arthritis, muscle spasms, minor strains and sprains; muscular relaxation; and the temporary increase of circulation relief of widespread pain associated with fibromyalgia; muscular relaxation; and the temporary increase of microcirculation.
 
The Society for Neuroscience 2013 Annual Meeting abstract program disclosed the 28-day AVACEN follow-up study produced a statistically significant reduction of over 40% in the widespread pain index and a reduction in average tender point counts from approximately 15 to 9
https://clinicaltrials.gov/ct2/show/NCT01619579?term=avacen&rank=1
 
The Med Writers, 218 Berenger Walk, Royal Palm Beach, FL 33414, USA 
The daily 10 min warming sessions, resulted in a decrease in widespread pain and weekly pain intensity symptoms for the majority of participants in Group A. Increasing the treatment to two 15 min sessions daily demonstrated a pronounced reduction of pain symptoms for the participants in Group B. Data were analyzed with either a paired t-test, or the Wilcoxon signed rank test. The pre- and post-treatment data for Group B indicated a statistically significant reduction (p=0.05) in TPC, WPI, and SS scores. Inspections of HRV and Cytokines found no statistically significant data. No adverse events were reported.